A 2000 Toyota Tundra ran off the left side of Highway U, nine miles north of Willow Springs and hit a tree.
The 44-year-old Summersville man driving was taken to Texas County Memorial Hospital with minor injuries.
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A 49-year-old Houston woman sustained moderate injuries when she ran off B highway four miles east of Houston, struck a ditch and a fence.
She was transported to Texas County Memorial Hospital for her injuries.
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